Graduated cum laude at the University of Rome “Sapienza” in 1995 and completed cum laude his residency in 2000. 

Under the mentorship of Prof. Plinio Rossi, he developed a strong interest in cardiovascular and interventional radiology. Between 2000 and 2001 he attended as a Visiting Resident the Cardiovascular and Interventional Radiology Unit at Stanford University under the mentorship of Prof. Michael D. Dake. In 2004 he attended the Visitor Program at the Miami Cardiac and Vascular Institute led by Prof. Barry T. Katzen.

He obtained the European Board of Interventional Radiology-EBIR in 2010 and, in 2014, the academic qualification as Full Professor of Radiology.

From 2001 to 2017 he served as consultant in the Vascular and Interventional Radiology Unit at the University Hospital in Rome; In 2013 he worked as “Oberarzt 1” in the Department of Clinical and Interventional Angiology at Inselspital-University Hospital-Bern-Switzerland. Since September 2017 is Director of Vascular and Interventional Radiology Department at “Careggi” University Hospital in Florence.

He performed more than 85.000 interventional procedures, including vascular and non-vascular interventions. His clinical activity focuses primarily on endovascular treatment of complex vascular diseases, peripheral arterial disease, aortic pathologies, carotid stenting, embolization, biliary interventions, AV malformations and TIPS.

He served as teaching professor in more than 150 training courses and has been actively involved in hands-on education and simulator-based training programs. 

Between 2004 and 2010 teaching professor at the European Surgical Institute in Hamburg; from 2008 to 2017 teaching professor of Interventional Radiology at the School of Radiology of the University of Rome “Sapienza”, and from 2010 to 2018 he also contributed to the PhD program in Angio-Cardiac-Thoracic Surgical Physiopathology and Imaging. Since 2017 teaching professor of Interventional Radiology in the Radiology Residency Program at the University of Florence.

He has also conducted numerous international proctorship and educational programs focusing on advanced endovascular technologies such as carotid stenting, drug-eluting devices, liquid embolic agents, aortic treatment and atherectomy systems.

Since 2000 he has participated in numerous international multicenter trials and registries. 

His scientific production includes 166 peer-reviewed publications, with an H-index of 40 and  5.445 citations. He has delivered over 600 invited lectures and presentations at international congresses. He is also the author of three specialized books and co-author to 18 additional books.

He serves on the editorial boards of several major journals in the field, including Cardiovascular and Interventional Radiology . Associate ediotor of  Journal of Vascular and Interventional Radiology, 2018 to 2026.  

He has held numerous leadership roles within major international scientific societies, particularly within the Cardiovascular and Interventional Radiological Society of Europe (CIRSE). Over the years he has served as member of the CIRSE Executive Committee, Chairman of the Standards of Practice Committee, and Chairman of the Program Committee of the CIRSE Annual Congress. He also introduced first IDEAS-Interdisciplinary Endovascular Aortic Symposium.  

In 2023 he founded the International Multidisciplinary Endovascular Forum (IM Endo Forum), aimed at promoting interdisciplinary collaboration and innovation in minimally invasive vascular therapies.